How many words start with LY?

25, from 5 letters up to 5. All of them are on this page.

What is the highest scoring word that start with LY?

LYMPH at 15 points in Scrabble, and LYMPH at 16 in Words With Friends, because the two games score the tiles differently.

LYAMS, LYARD, LYART, LYASE, LYCEA, LYCEE, LYCRA, LYING, LYMES, LYMPH and 15 more on this page.

There are 25 of them. The highest scoring is LYMPH at 15 points in Scrabble, and the set averages 9.3.

Most common words first, then the rest A to Z.

The most familiar words on this page and what they mean. Tap any word for its full entry, score and anagrams.

LYING noun the deliberate act of deviating from the truth
LYRIC adjective expressing deep emotion
LYMPH noun a thin coagulable fluid (similar to plasma but) containing white blood cells (lymphocytes) and chyle
LYCEE noun a school for students intermediate between elementary school and college
LYRES noun form of LYRE: a harp used by ancient Greeks for accompaniment
LYSIN noun any substance (such as an antibody) or agent that can cause lysis
LYSIS noun recuperation in which the symptoms of an acute disease gradually subside
LYSSA noun an acute viral disease of the nervous system of warm-blooded animals (usually transmitted by the bite of a rabid animal)

Definitions from Open English WordNet, CC BY 4.0.

All of them: Word lists.